6429-04-5
- Product Name：Tetrahydropapaverine Hydrochloride
- Molecular Formula：C20H25NO4.HCl
- Purity：99%
- Molecular Weight：379.884
Product Details;
CasNo： 6429-04-5
Molecular Formula： C20H25NO4.HCl
Appearance： White crystal powder
Buy Quality High Purity 99% Tetrahydropapaverine Hydrochloride 6429-04-5 Safe Delivery
- Molecular Formula:C20H25NO4.HCl
- Molecular Weight:379.884
- Appearance/Colour:White crystal powder
- Vapor Pressure:3.23E-09mmHg at 25°C
- Melting Point:213°C～215°C
- Refractive Index:1.549
- Boiling Point:475.8 °C at 760 mmHg
- Flash Point:202.7 °C
- PSA：48.95000
- Density:1.12g/cm3
- LogP:4.28130
Tetrahydropapaverine hydrochloride(Cas 6429-04-5) Usage
|
Uses |
Tetrahydropapaverine hydrochloride is an organic amine compound that can be used as atracuramide intermediate. |
|
Biological Activity |
Tetrahydropapaverine (Norlaudanosine), a TIQs, is an analogue of Salsolinol and Tetrahydropapaveroline, and has neurotoxic effects on dopamine neurons. |
InChI:InChI=1/C20H25NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-6,10-12,16,21H,7-9H2,1-4H3/t16-/m0/s1
6429-04-5 Relevant articles
Total synthesis of 8-epi-javaberine A and javaberine A
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, p. 1311 - 1321 (2016/11/07)
The total synthesis of berberine alkaloi...
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Sladkov, V. I.,Sazonova, N. M.,Grekova, G. S.,Kalistratov, S. G.,Sokolova, A. S.,et al.
, p. 47 - 50 (2007/10/02)
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Asymmetric Reduction of Cyclic Imines with Chiral Sodium Acyloxyborohydrides
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, p. 265 - 270 (2007/10/02)
Asymmetric reduction of prochiral cyclic...
Biodegradable neuromuscular blocking agents. Part 4. Atracurium besylate and related polyalkylene di-esters
Stenlake,Waigh,Dewar,et al.
, p. 515 - 524 (2007/10/02)
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6429-04-5 Process route
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- 5884-22-0
1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3.4-dihydroisoquinoline hydrochloride
-
- 6429-04-5,66820-84-6
1,2,3,4-tetrahydro-1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride
| Conditions | Yield |
|---|---|
|
With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 0.166667h; Inert atmosphere;
|
89% |
-
- 6957-27-3
3,4-dihydropapaverine
-
- 6429-04-5,66820-84-6
1,2,3,4-tetrahydro-1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride
| Conditions | Yield |
|---|---|
|
With sodium (S)-prolinate-borane; In tetrahydrofuran; for 240h; Ambient temperature;
|
78% |
|
With sodium tetrahydroborate; for 19h; Ambient temperature;
|
71% |
6429-04-5 Upstream products
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6957-27-3
3,4-dihydropapaverine
-
13074-31-2
Tetrahydropapaverine
-
93-40-3
(3,4-Dimethoxyphenyl)acetic acid
-
139-76-4
N-(3,4-dimethoxyphenethyl)-2-(3,4-dimethoxyphenyl)acetamide
6429-04-5 Downstream products
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523-02-4
2,3,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinoline
-
81182-07-2
3-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionic acid 4-{3-[1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionyloxy}-butyl ester; compound with oxalic acid
-
81165-42-6
3-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionic acid 3-{3-[1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionyloxy}-propyl ester; compound with oxalic acid
-
64228-78-0
pentamethylene bis(1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate) dioxalate
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