133238-87-6
- Product Name：5-nitro-2-butyl benzofuran
- Molecular Formula：C12H13NO3
- Purity：99%
- Molecular Weight：219.24
Product Details;
CasNo： 133238-87-6
Molecular Formula： C12H13NO3
Appearance： Pale yellow to yellow liquid
Buy High Grade 5-nitro-2-butyl benzofuran 133238-87-6 Offer with Lowest Price
- Molecular Formula:C12H13NO3
- Molecular Weight:219.24
- Appearance/Colour:Pale yellow to yellow liquid
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.586
- Boiling Point:329.721 °C at 760 mmHg
- Flash Point:153.21 °C
- PSA：58.96000
- Density:1.191 g/cm3
- LogP:4.20680
2-Butyl-5-nitrobenzofuran(Cas 133238-87-6) Usage
|
Chemical Properties |
Bright Yellow Low Melting Solid |
|
Uses |
Dronedarone intermediate. |
InChI:InChI=1/C12H13NO3/c1-2-3-4-11-8-9-7-10(13(14)15)5-6-12(9)16-11/h5-8H,2-4H2,1H3
133238-87-6 Relevant articles
Discovery of dronedarone and its analogues as NLRP3 inflammasome inhibitors with potent anti-inflammation activity
Chen, Hao,Chen, Xiuhui,Sun, Ping,Wu, Dan,Yue, Hu,Pan, Jintao,Li, Xinxuan,Zhang, Cheng,Wu, Xinyi,Hua, Lei,Hu, Wenhui,Yang, Zhongjin
supporting information, (2021/06/18)
Inhibiting NLRP3 inflammasome activation...
Benzofuran compound and application thereof
-
Paragraph 0053-0055; 0059-0061, (2021/08/06)
The invention provides a benzofuran comp...
Preparation method of key intermediate of dronedarone
-
Paragraph 0021; 0022, (2019/10/02)
The invention relates to a preparation m...
Microwave-assisted synthesis of (2-butyl-5-nitrobenzo[b]furan-3-yl)-[4-(substituted ethynyl)phenyl]methanones
Parmar, Nilesh D.,Hadiyal, Sanjay D.,Kapupara, Vimal H.,Joshi, Hitendra S.
, p. 143 - 153 (2018/10/26)
We report a new method for the efficient...
133238-87-6 Process route
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335153-21-4
2-(2-formyl-4-nitrophenoxy)hexanoic acid
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133238-87-6
2-(n-butyl)-5-nitrobenzofuran
| Conditions | Yield |
|---|---|
|
With
sodium acetate; acetic anhydride; acetic acid;
for 3h;
Heating;
|
-
-
5445-19-2
methyl 2-bromohexanoate
-
-
133238-87-6
2-(n-butyl)-5-nitrobenzofuran
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 3 steps
1: 87 percent / K2CO3 / dimethylformamide / 3.5 h / 92 - 94 °C
2: 80 percent / NaOH / Heating
3: acetic anhydride; sodium acetate; acetic acid / 3 h / Heating
With
sodium hydroxide; sodium acetate; acetic anhydride; potassium carbonate; acetic acid;
In
N,N-dimethyl-formamide;
|
133238-87-6 Upstream products
-
335153-21-4
2-(2-formyl-4-nitrophenoxy)hexanoic acid
-
5445-19-2
methyl 2-bromohexanoate
-
97-51-8
5-Nitrosalicylaldehyde
-
847869-79-8
methyl 2-(2-formyl-4-nitrophenoxy)butanoate
133238-87-6 Downstream products
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141627-42-1
(2-butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone
-
141645-45-6
3-[4-(3-chloro propionamido)benzoyl] 2-n-butyl 5-nitro benzofuran
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141645-16-1
2-n-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran
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856758-04-8
2-n-butyl-5-nitro-3-(2'-methoxy)-acetophenonebenzofuran
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