93793-83-0

  • Product Name:Roxatidine Acetate Hydrochloride
  • Molecular Formula:C19H28N2O4.ClH
  • Purity:99%
  • Molecular Weight:384.903
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Product Details;

CasNo: 93793-83-0

Molecular Formula: C19H28N2O4.ClH

Buy Quality 99% Pure Roxatidine Acetate Hydrochloride 93793-83-0 Efficient Delivery

  • Molecular Formula:C19H28N2O4.ClH
  • Molecular Weight:384.903
  • Vapor Pressure:1.29E-11mmHg at 25°C 
  • Melting Point:145-146° 
  • Boiling Point:537.3 °C at 760 mmHg 
  • Flash Point:278.7 °C 
  • PSA:67.87000 
  • LogP:3.25150 

Roxatidine acetate hydrochloride(Cas 93793-83-0) Usage

Description

Roxatidine acetate hydrochloride is an H2 antagonist, differing considerably in structure from other marketed agents(cimetidine, ranitidine and famotidine) in this category. It is useful in the treatment of gastric, duodenal and anastomotic ulcers, Zollinger-Ellison syndrome and peptic esophagitis.

Chemical Properties

White Solid

Originator

Teikoku Hormone (Japan)

Uses

antibacterial

Brand name

ALTAT

InChI:InChI=1/C19H28N2O4.ClH/c1-16(22)25-15-19(23)20-9-6-12-24-18-8-5-7-17(13-18)14-21-10-3-2-4-11-21;/h5,7-8,13H,2-4,6,9-12,14-15H2,1H3,(H,20,23);1H

93793-83-0 Relevant articles

A preparation method for rosacea acetate hydrochloride

-

, (2021/12/07)

The present invention relates to the fie...

Preparation method of high-purity medicinal roxatidine acetate hydrochloride

-

Paragraph 0038-0039; 0044-0045, (2021/02/06)

The invention discloses a preparation me...

Preparation method of roxatidine acetate hydrochloride

-

Paragraph 0052; 0083; 0090-0097; 0104-0111; 0118-0124, (2020/05/01)

The invention relates to a preparation m...

Novel preparation method of intermediate namely 3-(1-piperidine methyl)phenol of roxatidine acetate hydrochloride

-

Paragraph 0074-0077, (2018/04/02)

The invention relates to a preparation m...

93793-83-0 Process route

acetic anhydride
108-24-7

acetic anhydride

2-hydroxy-N-[3-[3-(piperidinomethyl)phenoxy]propyl] acetamide
78273-80-0

2-hydroxy-N-[3-[3-(piperidinomethyl)phenoxy]propyl] acetamide

Gastralgin
93793-83-0

Gastralgin

Conditions
Conditions Yield
acetic anhydride; 2-hydroxy-N-[3-[3-(piperidinomethyl)phenoxy]propyl] acetamide; With acetic acid; for 2h; Reflux;
With hydrogenchloride; In water; ethyl acetate; acetone; at 0 - 5 ℃;
89.8%
piperidine
110-89-4

piperidine

(3-(3-bromomethylphenoxy)propylamino)-2-oxoethyl acetate

(3-(3-bromomethylphenoxy)propylamino)-2-oxoethyl acetate

Gastralgin
93793-83-0

Gastralgin

Conditions
Conditions Yield
piperidine; (3-(3-bromomethylphenoxy)propylamino)-2-oxoethyl acetate; In acetonitrile; for 8h; Reflux; Large scale;
With hydrogenchloride; In water; acetone; at -5 - 5 ℃; for 1h; pH=2 - 3; Solvent; Inert atmosphere; Large scale;
81.18%

93793-83-0 Upstream products

  • 127-08-2
    127-08-2

    potassium acetate

  • 108441-34-5
    108441-34-5

    N-<3-<3-(1-piperidinylmethyl)phenoxy>propyl>chloroacetamide

  • 110-89-4
    110-89-4

    piperidine

  • 73279-04-6
    73279-04-6

    3-[1-piperidinylmethyl]phenol

93793-83-0 Downstream products

  • 1338084-91-5
    1338084-91-5

    C19H28N2O4*C42H70O35

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