What is the Megestrol acetate?

Megestrol acetate is Crystalline Solid, while it's Molecular Formula is C24H32O4. Crystalline Solid Megestrol acetate (Megace), a semi-synthetic progestational steroid, is the most effective known appetite stimulant at present. Previously used in patients with cancer and acquired immunodeficiency syndrome, only a few studies have considered the applicability of this drug in malnourished older persons. Megestrol acetate is useful if profound anorexia is the main manifestation of cachexia and if expected survival is weeks to months. Megace has been shown to significantly increase appetite, but not survival. In patients with a shorter predicted survival, a brief course of corticosteroids may be useful to stimulate appetite and have positive effects on nausea, pain, and asthenia.

What is the CAS number for Megestrol acetate?

The CAS number of Megestrol acetate is 595-33-5.

What is Megestrol acetate (595-33-5) used for?

Megestrol Acetate is the acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic and antineoplastic activity. It is frequently used in the treatment of patients with metastatic breast cancer. It is generally well tolerated, except that it may cause undesirable weight gain. Subsequently, it was shown that megestrol acetate produced weight gain in a variety of cachectic cancer patients. Significant reduction inserum levels of IL-1a and b,IL-2,IL-6, and TNF-o were observed in cancer patientstreated with megestrol acetate which may bear on the mechanism of improved appetite and body weight gain.It has also been postulated that the effect is, at least in part,mediated by NPY,a potent central appetite stimulant.InChI:InChI=1/C23H30O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h5-6,13,18-20H,7-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1

Product classification

Hormones and steriods major pro

Medroxyprogesterone acetate intermediates

Progesterone intermediate

Cyproterone acetate intermediate

Deflazacort intermediate

Desogestrel intermediate

Finasteride intermediate
Major Products

Rocuronium bromide intermediate

Ubrogepant intermediate

Rimegepant intermediate

Indacaterol intermedaite

Dapagliflozin intermediate
Others

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595-33-5

Product Name：Megestrol Acetate
Molecular Formula：C₂₄H₃₂O₄
Purity：99%
Molecular Weight：384.516

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Product Details;

CasNo： 595-33-5

Molecular Formula： C₂₄H₃₂O₄

Appearance： Crystalline Solid

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Hormones and steriods major pro

Product classification

Medroxyprogesterone acetate intermediates

Progesterone intermediate

Cyproterone acetate intermediate

Deflazacort intermediate

Desogestrel intermediate

Finasteride intermediate

Rocuronium bromide intermediate

Ubrogepant intermediate

Rimegepant intermediate

Indacaterol intermedaite

Dapagliflozin intermediate

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595-33-5

Product Details;

Relevant Products