98319-24-5
- Product Name：Dihydroproscar(F9)
- Molecular Formula：C23H38N2O2
- Purity：99%
- Molecular Weight：374.567
Product Details;
CasNo： 98319-24-5
Molecular Formula： C23H38N2O2
Dihydroproscar(F9) 98319-24-5 with purity >99% Low price in stock
- Molecular Formula:C23H38N2O2
- Molecular Weight:374.567
- Vapor Pressure:0mmHg at 25°C
- Melting Point:273-275 °C
- Refractive Index:1.514
- Boiling Point:569.397 °C at 760 mmHg
- PKA:15.94±0.70(Predicted)
- Flash Point:171.728 °C
- PSA：58.20000
- Density:1.051 g/cm3
- LogP:4.75820
Dihydroproscar(Cas 98319-24-5) Usage
InChI:InChI=1/C23H38N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h14-18H,6-13H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
98319-24-5 Relevant articles
Synthesis and comprehensive structural and physicochemical characterization of dutasteride hydrochloride hydrate solvates
Górecki, Marcin,Dziedzic, Alicja,Luboradzki, Roman,Ostaszewska, Anna,Frelek, Jadwiga,Szczepek, Wojciech J.
, p. 72 - 80 (2017/06/30)
Four crystalline dutasteride hydrochlori...
A synthetic 3-carbonyl-4-nitrogen mixed male steroid -17 β derivative method
-
Paragraph 0056-0065; 0068-0069, (2017/01/26)
The invention discloses a method for syn...
Impurities in finasteride: Identification, synthesis, characterization and control of potential carry-over impurities from reagents used for the process
Mohanty, Sandeep,Kumar, B. Pavan,Karmakar, Arun Chandra
, p. 4375 - 4380 (2014/08/05)
An assessment of the impurity profile of...
PROCESS FOR THE PREPARATION OF 17-N-SUBSTITUTED-CARBAMOYL-4-AZA-ANDROST-1 -EN-3-ONES
-
Page/Page column 13-14, (2008/12/08)
The present invention relates to a proce...
98319-24-5 Process route
-
-
103335-55-3,1430804-94-6
3-oxo-4-aza-5α-androstane-17β-carboxylic acid
-
-
75-64-9
tert-butylamine
-
-
98319-24-5
dihydro-finasteride
| Conditions | Yield |
|---|---|
|
3-oxo-4-aza-5α-androstane-17β-carboxylic acid;
With
1,1'-carbonyldiimidazole;
In
1-methyl-pyrrolidin-2-one;
at 20 - 30 ℃;
for 5h;
tert-butylamine;
With
2-hydroxypyridin;
In
1-methyl-pyrrolidin-2-one;
at 100 ℃;
for 6h;
under 517.162 - 1034.32 Torr;
|
90% |
|
3-oxo-4-aza-5α-androstane-17β-carboxylic acid;
With
pyridine;
In
chloroform; N,N-dimethyl-formamide;
at 20 ℃;
for 0.5h;
With
thionyl chloride;
In
chloroform; N,N-dimethyl-formamide;
at 20 ℃;
for 3h;
Cooling;
tert-butylamine;
With
dmap;
In
chloroform; N,N-dimethyl-formamide;
at 20 ℃;
for 20h;
|
84% |
|
3-oxo-4-aza-5α-androstane-17β-carboxylic acid;
With
benzotriazol-1-ol;
In
dichloromethane;
at 40 ℃;
for 5h;
Heating / reflux;
tert-butylamine;
at 30 ℃;
for 4h;
|
|
|
With
benzotriazol-1-ol; dicyclohexyl-carbodiimide;
In
methanol;
|
-
-
75-64-9
tert-butylamine
-
-
98319-24-5
dihydro-finasteride
| Conditions | Yield |
|---|---|
|
3-oxo-4-aza-5α-androstane-17β-carboxylic acid;
With
1,1'-carbonyldiimidazole;
In
1-methyl-pyrrolidin-2-one;
at 20 - 30 ℃;
for 5h;
tert-butylamine;
With
2-hydroxypyridin;
In
1-methyl-pyrrolidin-2-one;
at 100 ℃;
for 6h;
under 517.162 - 1034.32 Torr;
|
90% |
98319-24-5 Upstream products
-
75-64-9
tert-butylamine
-
103335-50-8
S-2-pyridyl 3-oxo-4-aza-5α-androstane-17β-thiocarboxylate
-
104214-27-9
benzotriazol-1'-yl 3-oxo-4-aza-5α-androstane-17β-carboxylate
-
166896-74-8
N-tert-butyl-3-oxo-4-aza-5-androsten-17β-formamide
98319-24-5 Downstream products
-
98319-26-7
finasteride
-
684215-49-4
N-tert-butyl-2-phenylsulfenyl-3-oxo-4-aza-5α-androstane-17β-carboxamide
-
123-31-9
hydroquinone
-
943823-26-5
C31H44N2O4
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