1421373-66-1
- Product Name：Osimertinib mesylate
- Molecular Formula：C29H37N7O5S
- Purity：99%
- Molecular Weight：595.723
Product Details;
CasNo： 1421373-66-1
Molecular Formula： C29H37N7O5S
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What is the AZD-9291 (Mesylate) ?
AZD-9291 (Mesylate) is , while it's Molecular Formula is C28H33N7O2.CH4O3S. AZD-9291 Mesylate is a potent and selective epidermal growth factor receptor (EGFR) inhibitor.
What is the CAS number for AZD-9291 (Mesylate) ?
The CAS number of AZD-9291 (Mesylate) is 1421373-66-1.
More information of AZD-9291 (Mesylate) 1421373-66-1 are:
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Synonyms |
AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib mesylate;Mereletinib mesylate;Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291) |
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CAS Number |
1421373-66-1 |
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Molecular Formula |
C28H33N7O2.CH4O3S |
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Molecular Weight |
595.723 |
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HS CODE |
29339900 |
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PSA |
153.79000 |
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LogP |
5.81710 |
What is AZD-9291 (Mesylate) (1421373-66-1) used for?
Osimertinib is active against exon 19 deletions, exon 21 mutations, and also the exon 20 T790M mutations. It is preferentially selective for mutated EGFR, and therefore toxicity at therapeutic doses is lower than for first- and second-generation agents. Notably, osimertinib is able to cross the blood-brain barrier, making it active against disease in the CNS.
Articles related to AZD-9291 (Mesylate):
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Article |
Source |
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AN IMPROVED PROCESS FOR THE PREPARATION OF OSIMERTINIB MESYLATE |
- Paragraph 6; 7, (2021/06/11) |
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Synthetic method of osimertinib AZD9291 |
- Paragraph 0075-0081, (2019/01/23) |
How to get the best price on AZD-9291 (Mesylate)?
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