461432-23-5
- Product Name：5-bromo-2-chloro-4’-ethoxydiphenylmethane
- Molecular Formula：C15H14BrClO
- Purity：99%
- Molecular Weight：325.633
Product Details;
CasNo： 461432-23-5
Molecular Formula： C15H14BrClO
Buy High Grade Wholesale 5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5 Fast Delivery
- Molecular Formula:C15H14BrClO
- Molecular Weight:325.633
- Boiling Point:392.976 °C at 760 mmHg
- Flash Point:191.465 °C
- PSA：9.23000
- Density:1.371 g/cm3
- LogP:5.09200
5-bromo-2-chloro-4’-ethoxydiphenylmethane (Cas 461432-23-5) Usage
|
Uses |
5-Bromo-2-chloro-4'-ethoxydiphenylmethane is a hydrocarbon derivative that can be used as an intermediate for dapagliflozin, a synthetic antidiabetic medicine. |
461432-23-5 Relevant articles
Synthesis method for preparing 5-bromo-2-chloro-4'-ethoxydiphenylmethane
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, (2022/04/08)
The present invention relates to a metho...
PREPARATION OF HIGHLY PURE AMORPHOUS DAPAGLIFLOZIN
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Page/Page column 24, (2021/12/13)
A novel and improved process for the pre...
Synthesis method of dapagliflozin intermediate 5-bromo-2-chloro-4 '-ethoxydiphenylmethane
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, (2020/04/06)
The invention discloses a synthesis meth...
Preparation method of 5-bromo-2-chloro-4 '-ethoxydiphenylmethane
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Paragraph 0034; 0038; 0044-0060, (2020/09/23)
The invention relates to a preparation m...
461432-23-5 Process route
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5-bromo-2-amino-4'-ethoxydiphenylmethane
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![4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene](/upload/2023/9/e18fa71f-4c21-4a2b-87d7-8ceb41fe922a.png)
- 461432-23-5
4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene
| Conditions | Yield |
|---|---|
|
5-bromo-2-amino-4'-ethoxydiphenylmethane; With hydrogenchloride; sodium nitrite; In water; at -5 - 0 ℃; for 3h; Large scale;
With hydrogenchloride; copper(l) chloride; In water; at 20 - 80 ℃; for 4h; Large scale;
|
83% |
|
5-bromo-2-amino-4'-ethoxydiphenylmethane; With hydrogenchloride; sodium nitrite; In water; at -5 ℃; for 3h; Industrial scale;
With copper(l) chloride; In water; at 20 - 80 ℃; for 4h; Industrial scale;
|
83% |
|
5-bromo-2-amino-4'-ethoxydiphenylmethane; With hydrogenchloride; sodium nitrite; In water; at -5 - 0 ℃; for 3h; Large scale;
With hydrogenchloride; copper(l) chloride; In water; at 20 - 80 ℃; for 3h; Large scale;
|
79% |
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4-bromo-1-chloro-2-(chloromethyl)benzene
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- 103-73-1
Phenetole
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- 461432-23-5
4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene
| Conditions | Yield |
|---|---|
|
With aluminum (III) chloride; In ethyl acetate; at 78 ℃; for 9h; Cooling with ice; Large scale;
|
89% |
461432-23-5 Upstream products
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461432-22-4
(5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone
-
107-06-2
1,2-dichloro-ethane
-
21739-92-4
5-bromo-2-chlorobenzoic acid
-
103-73-1
Phenetole
461432-23-5 Downstream products
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461432-24-6
(3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
-
960494-15-9
C33H57ClO7Si4
-
864070-18-8
4-(5-bromo-2-chlorobenzyl)phenol
-
714269-57-5
(2S,3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)-2-methoxy-tetrahydropyran-3,4,5-triol
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