53292-89-0
- Product Name：Trans-4-(boc-amino)cyclohexanecarboxylic acid
- Molecular Formula：C12H21NO4
- Purity：99%
- Molecular Weight：243.303
Product Details;
CasNo： 53292-89-0
Molecular Formula： C12H21NO4
Factory Supply Top Purity Trans-4-(boc-amino)cyclohexanecarboxylic acid 53292-89-0 Competitive Price
- Molecular Formula:C12H21NO4
- Molecular Weight:243.303
- Vapor Pressure:2.12E-07mmHg at 25°C
- Melting Point:181.0 to 185.0 °C
- Refractive Index:1.493
- Boiling Point:396.7 °C at 760 mmHg
- PKA:4.76±0.10(Predicted)
- Flash Point:193.7 °C
- PSA：75.63000
- Density:1.13 g/cm3
- LogP:2.54540
BOC-1,4-TRANS-ACHC-OH(Cas 53292-89-0) Usage
|
Chemical Properties |
White solid |
|
Uses |
Boc-trans-4-aminocyclohexanecarboxylic acid is a reagent to synthesize N-myristoyltransferase and CD38 inhibitors. |
InChI:InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13-9-6-4-8(5-7-9)10(14)15/h8-9H,4-7H2,1-3H3,(H,13,16)(H,14,15)/t8-,9-
53292-89-0 Relevant articles
Discovery of Hydroxyamidine Derivatives as Highly Potent, Selective Indoleamine-2,3-dioxygenase 1 Inhibitors
Jin, Fangfang,Hu, Qiyue,Fei, Hongbo,Lv, Hejun,Wang, Shenglan,Gui, Bin,Zhang, Junzhen,Tu, Wangyang,Zhang, Yun,Zhang, Lei,Wan, Hong,Zhang, Limin,Hu, Bin,Yang, Fanglong,Bai, Chang,He, Feng,Zhang, Lianshan,Tao, Weikang
supporting information, p. 195 - 201 (2021/02/06)
In this study, a series of novel hydroxy...
Preparation method of trans 4 - (tert-butyloxycarbonylamino) cyclohexanecarboxylic acid and intermediate thereof
-
Paragraph 0043; 0046-0047; 0050, (2021/09/21)
The invention provides a preparation met...
BIFUNCTIONAL DEGRADERS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES AND THERAPEUTIC USE THEREOF
-
Page/Page column 56-57, (2021/08/27)
The present disclosure provides bifuncti...
Compound serving as protein kinase inhibitor and application of compound
-
Paragraph 0330-0333, (2021/04/07)
The invention discloses a compound used ...
53292-89-0 Process route
-
- 24424-99-5
di-tert-butyl dicarbonate
-
- 1776-53-0,3685-23-2,3685-25-4,57043-03-5,66762-20-7
trans-4-aminocyclohexanecarboxylic acid
-
- 53292-90-3,130309-46-5,53292-89-0
trans-4-(tert-butoxycarbonylamino)cyclohexanoic acid
| Conditions | Yield |
|---|---|
|
With triethylamine;
|
95% |
|
With sodium hydroxide; In 1,4-dioxane; water; at 0 - 20 ℃; for 2h;
|
95% |
|
With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;
|
95% |
|
di-tert-butyl dicarbonate; trans-4-aminocyclohexanecarboxylic acid; With sodium hydroxide; In water; tert-butyl alcohol; at 0 - 20 ℃;
With hydrogenchloride; In hexane; water; pH=~ 6;
|
82.8% |
|
With sodium hydroxide; In tert-butyl alcohol;
|
66% |
|
trans-4-aminocyclohexanecarboxylic acid; With sodium hydroxide; In 1,4-dioxane;
di-tert-butyl dicarbonate; In 1,4-dioxane; at 0 - 20 ℃; for 5h;
|
-
amino}cyclohexane‐1‐carboxylate](/upload/2023/9/fafaf95a-e1c0-4d5e-8601-71238a12d3da.png)
- 400899-07-2
methyl (1r,4r)‐4‐{[(tert‐butoxy)carbonyl](methyl)amino}cyclohexane‐1‐carboxylate
-
- 53292-90-3,130309-46-5,53292-89-0
trans-4-(tert-butoxycarbonylamino)cyclohexanoic acid
| Conditions | Yield |
|---|---|
|
With lithium hydroxide; In tetrahydrofuran; at 20 ℃;
|
96% |
53292-89-0 Upstream products
-
24424-99-5
di-tert-butyl dicarbonate
-
1776-53-0
trans-4-aminocyclohexanecarboxylic acid
-
150-13-0
4-amino-benzoic acid
-
146307-51-9
methyl (1R,4R)-4-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate
53292-89-0 Downstream products
-
146307-51-9
methyl (1R,4R)-4-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate
-
615568-05-3
C21H28N4O4
-
1357278-98-8
tert-butyl (1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexylcarbamate
-
1357278-99-9
(1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexanamine
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