36421-15-5
- Product Name：1-dibutylamino-3-chloropropane
- Molecular Formula：C11H24ClN
- Purity：99%
- Molecular Weight：205.771
Product Details;
CasNo： 36421-15-5
Molecular Formula： C11H24ClN
Buy Quality 99% Pure 1-dibutylamino-3-chloropropane 36421-15-5 Fast Shipping
- Molecular Formula:C11H24ClN
- Molecular Weight:205.771
- Vapor Pressure:0.0185mmHg at 25°C
- Refractive Index:1.45
- Boiling Point:253.2 °C at 760 mmHg
- PKA:9.39±0.50(Predicted)
- Flash Point:106.9 °C
- PSA：3.24000
- Density:0.899 g/cm3
- LogP:3.51750
N-(3-chloropropyl)dibutylamine(Cas 36421-15-5) Usage
|
Uses |
N-Butyl-N-(3-chloropropyl)butan-1-amine acts as a reagent in the process for the production of dronedarone hydrochloride, an antiarrhythmia drug. Impurity of Butoprozine which is an antiarrhythmic drug. |
InChI:InChI=1/C11H24ClN/c1-3-5-9-13(10-6-4-2)11-7-8-12/h3-11H2,1-2H3
36421-15-5 Relevant articles
-
Blicke,Otsuki
, p. 2435 (1941)
-
Efficient Syntheses of Diverse, Medicinally Relevant Targets Planned by Computer and Executed in the Laboratory
Klucznik, Tomasz,Mikulak-Klucznik, Barbara,McCormack, Michael P.,Lima, Heather,Szymku?, Sara,Bhowmick, Manishabrata,Molga, Karol,Zhou, Yubai,Rickershauser, Lindsey,Gajewska, Ewa P.,Toutchkine, Alexei,Dittwald, Piotr,Startek, Micha? P.,Kirkovits, Gregory J.,Roszak, Rafa?,Adamski, Ariel,Sieredzińska, Bianka,Mrksich, Milan,Trice, Sarah L.J.,Grzybowski, Bartosz A.
supporting information, p. 522 - 532 (2018/03/21)
The Chematica program was used to autono...
Convergent synthesis of dronedarone, an antiarrhythmic agent
Okitsu, Takashi,Ogasahara, Mizuki,Wada, Akimori
, p. 1149 - 1153 (2016/08/11)
We have developed a convergent synthesis...
METHOD FOR PREPARING 3-KETO-BENZOFURANE DERIVATIVES
-
Paragraph 0060, (2013/07/05)
The invention relates to a method for pr...
PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5
-
Paragraph 0116, (2013/07/05)
The disclosure relates to a process for ...
36421-15-5 Process route
-
-
2050-51-3
3-dibutylaminopropanol
-
-
36421-15-5
dibutyl-(3-chloro-propyl)-amine
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
In
chloroform;
for 7h;
Reflux;
|
94% |
|
With
thionyl chloride;
In
chloroform;
at 20 ℃;
for 1h;
Reflux;
Inert atmosphere;
|
89% |
|
With
thionyl chloride; chloroform;
|
|
|
With
thionyl chloride; benzene;
|
|
|
With
hydrogenchloride; thionyl chloride;
In
chloroform;
|
-
-
115555-77-6
1-chloro-3-(di-n-butylamino)-propane hydrochloride
-
-
36421-15-5
dibutyl-(3-chloro-propyl)-amine
| Conditions | Yield |
|---|---|
|
With
ammonia;
In
water;
at 20 - 24 ℃;
for 1.41667h;
pH=11;
|
99.4% |
|
With
ammonia;
In
water;
at 18 - 24 ℃;
for 0.75h;
|
99.4% |
|
With
ammonia;
In
water;
at 20 ℃;
for 0.25h;
|
9.99 g |
|
With
ammonium hydroxide;
In
water;
at 20 - 25 ℃;
for 0.25h;
|
36421-15-5 Upstream products
-
2050-51-3
3-dibutylaminopropanol
-
111-92-2
dibutylamine
-
109-70-6
1.3-chlorobromopropane
-
115555-77-6
1-chloro-3-(di-n-butylamino)-propane hydrochloride
36421-15-5 Downstream products
-
6344-40-7
2-(3-dibutylamino-propyl)-acetoacetic acid ethyl ester
-
5417-24-3
4-dibutylamino-butyronitrile
-
94431-56-8
5-Dibutylamino-2-phenyl-valeronitril
-
79285-57-7
(1-Chloro-2-methyl-indolizin-3-yl)-[4-(3-dibutylamino-propoxy)-phenyl]-methanone; compound with oxalic acid
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-
-
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