52-76-6
- Product Name:Lynestrenol
- Molecular Formula:C20H28O
- Purity:99%
- Molecular Weight:284.442
Product Details;
CasNo: 52-76-6
Molecular Formula: C20H28O
Factory Supply Industrial Grade Lynestrenol 52-76-6 with Best Price
- Molecular Formula:C20H28O
- Molecular Weight:284.442
- Vapor Pressure:4.77E-08mmHg at 25°C
- Melting Point:158 °C
- Refractive Index:1.567
- Boiling Point:399.6 °C at 760 mmHg
- PKA:13.12±0.40(Predicted)
- Flash Point:176.9 °C
- PSA:20.23000
- Density:1.08 g/cm3
- LogP:4.31350
Lynestrenol(Cas 52-76-6) Usage
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World Health Organization (WHO) |
Lynestrenol, a synthetic progestogen, was introduced in the early 1960s as a component in oral contraceptive preparations. In 1967, as a result of new regulations required by the United States Food and Drug Administration, lynestrenol was submitted to long-term toxicity studies and by the early 1970s it was shown to be associated with an increased incidence of mammary tumours in beagle bitches which led to its withdrawal by at least one regulatory authority. Subsequently the validity of the beagle bitch model as a predictor of carcinogenicity of steroid contraceptives has been contested by many national regulatory authorities and lynestrenol remains available in some countries for contraceptive and other purposes. (Reference: (WHODI) WHO Drug Information, 1-3, 5-7, 1984) |
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Safety Profile |
An experimental teratogen.Experimental reproductive effects. Human reproductiveeffects by ingestion and implant routes: menstrual cyclechanges or disorders, female fertility index, other fertilitychanges and effects on females. Questionable carcinoge |
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Brand name |
Anacycline 101;Anacylin 101;Anacylin 28;Ancylin;Athilyn;Endometril;Exluton (a);Fysiognens;Fysionorm;Gestrol;Lindiol 2.5;Lyn_ratiopharm;Lyn_ratiophram_sequenz;Lyndeol;Lyndile tt;Lyndiol e.;Lyndiolett;Lynoenstrenol;Lyn-ratiopharm;Mini pregnon;Minifol;Minilyn;Neo lyndiol;Neo-lindiol;Neo-lynobol;Nonovulet;Noracyclin 22;Normophasic;Novostat;Org 485-50;Orgaluton;Orgametrol;Ovamezzo;Ovanone;Ovanon-e;Ovariostat;Ovoresta micro;Ovostat-28;Ovostat-micro;Phasicon;Physiostat;Physistat;Pregnon-28;Restovar. |
InChI:InChI=1/C20H28O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-12-19(18,20)2/h1,6,15-18,21H,4-5,7-13H2,2H3/t15-,16+,17+,18-,19-,20+/m0/s1
52-76-6 Relevant articles
Process for the production of 3-deoxy-4-ene steroids
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, (2008/06/13)
A process for the production of 3-deoxy-...
52-76-6 Process route
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68-22-4
norethisterone
-
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7440-44-0
pyrographite
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-
52-76-6
lynestrenol
| Conditions | Yield |
|---|---|
|
In
acetone;
|
-
-
3646-28-4
4-Estren-17-one
-
-
52-76-6
lynestrenol
| Conditions | Yield |
|---|---|
|
With
isopropyl alcohol;
|
52-76-6 Upstream products
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3646-28-4
4-Estren-17-one
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3646-30-8
(+)-17β-hydroxyester-4-ene
-
68-22-4
norethisterone
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7440-44-0
pyrographite
52-76-6 Downstream products
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1253379-05-3
19-nor-17α-pregn-4-en-20-yn-3β,6β,17β-triol
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51724-44-8
19-nor-17α-pregn-4-en-20-yn-3-one-6β,17β-diol
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1236-00-6
19-nor-17α-pregn-4-en-20-yn-3-one-10β,17β-diol
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