2322-77-2

  • Product Name:18-Methyl-3-methoxy-2, 5(10)-estradien-17-one
  • Molecular Formula:C20H28O2
  • Purity:99%
  • Molecular Weight:300.441
InquiryAdd to cart

Product Details;

CasNo: 2322-77-2

Molecular Formula: C20H28O2

Appearance: White to Off-White Crystalline Powder

Factory supply 18-Methyl-3-methoxy-2, 5(10)-estradien-17-one 2322-77-2 with low price

  • Molecular Formula:C20H28O2
  • Molecular Weight:300.441
  • Appearance/Colour:White to Off-White Crystalline Powder 
  • Vapor Pressure:3.21E-08mmHg at 25°C 
  • Melting Point:≥170oC 
  • Refractive Index:1.551 
  • Boiling Point:448 °C at 760 mmHg 
  • Flash Point:188.8 °C 
  • PSA:26.30000 
  • Density:1.09 g/cm3 
  • LogP:4.80260 

Methoxydienone(Cas 2322-77-2) Usage

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C20H28O2/c1-3-20-11-10-16-15-7-5-14(22-2)12-13(15)4-6-17(16)18(20)8-9-19(20)21/h5,16-18H,3-4,6-12H2,1-2H3/t16-,17-,18+,20+/m1/s1

2322-77-2 Relevant articles

SILICA GEL PROMOTED SELECTIVE HYDROLYSIS OF 3-METHOXY-2,5(10)-DIENE STEROIDS

Lui, Li-Gong,Zhang, Tong,Li, Zhen-Su

, p. 2999 - 3006 (2007/10/03)

Hydrolysis of 3-methoxy-2,5(10)-diene st...

Total synthesis with a chirogenic opening move demonstrated on steroids with estrane or 18a-homoestrane skeleton

Quinkert,Del Grosso,Doring,Doring,Schenkel,Bauch,Dambacher,Bats,Zimmermann,Durner

, p. 1345 - 1391 (2007/10/02)

A concept of first choice for the synthe...

Aromatization of dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17β-ol

Sharma,Chatterjee

, p. 158 - 159 (2007/10/02)

-

Total-synthesis of (-)-norgestrel

Baier,Durner,Quinkert

, p. 1054 - 1068 (2007/10/02)

-

2322-77-2 Process route

dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17β-ol
1038-28-4,5772-35-0,14507-49-4,77209-48-4,85798-56-7

dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17β-ol

dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one
2322-77-2,6236-40-4,17092-08-9,19640-64-3

dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one

Conditions
Conditions Yield
With molecular sieve; aluminum isopropoxide; butanone; In benzene;
76%
With cyclohexanone; aluminum isopropoxide; In toluene; Heating;
2-Ethyl-3-vinyl-cyclopentanone

2-Ethyl-3-vinyl-cyclopentanone

dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one
2322-77-2,6236-40-4,17092-08-9,19640-64-3

dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one

Conditions
Conditions Yield
Multi-step reaction with 5 steps
1: 80 percent NaH, Et3N / 1,2-dimethoxy-ethane; paraffin / 1.) 3.5 h, reflux; 2.) 40 min
2: 1.) 2,4,6-trimethylphenol, pyridine; 2.) oxalic acid / 1.) methylcyclohexane, 13.5 h, 98 deg C, irradiation
3: 99 percent / LiAlH4 / diethyl ether
4: 62 percent / K, aniline, NH3 / tetrahydrofuran / 1 h
5: 76 percent / 2-butanone, aluminium isopropylate, mol. sieve / benzene
With pyridine; lithium aluminium tetrahydride; molecular sieve; Mesitol; ammonia; oxalic acid; aluminum isopropoxide; sodium hydride; triethylamine; aniline; butanone; In tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; paraffin; benzene;
Multi-step reaction with 6 steps
1: 86 percent / TsOH*H2O / 14 h / Heating
2: 1.) 1.3 M MeLi; 2.) 10 percent H2SO4 / 1.) Et2O, 0.5 h; -20 deg C, 3h; 2.) Et2O, 14 h, RT
3: 1.) 2,4,6-trimethylphenol, pyridine; 2.) oxalic acid / 1.) methylcyclohexane, 13.5 h, 98 deg C, irradiation
4: 99 percent / LiAlH4 / diethyl ether
5: 62 percent / K, aniline, NH3 / tetrahydrofuran / 1 h
6: 76 percent / 2-butanone, aluminium isopropylate, mol. sieve / benzene
With pyridine; lithium aluminium tetrahydride; molecular sieve; Mesitol; sulfuric acid; ammonia; methyllithium; oxalic acid; aluminum isopropoxide; toluene-4-sulfonic acid; aniline; butanone; In tetrahydrofuran; diethyl ether; benzene;
Multi-step reaction with 5 steps
1: 1.) NaH, 2.) H2SO4 / 1.) DME, paraffin oil; Et2O; 2.) MeOH
2: 1.) 2,4,6-trimethylphenol, pyridine; 2.) oxalic acid / 1.) methylcyclohexane, 13.5 h, 98 deg C, irradiation
3: 99 percent / LiAlH4 / diethyl ether
4: 62 percent / K, aniline, NH3 / tetrahydrofuran / 1 h
5: 76 percent / 2-butanone, aluminium isopropylate, mol. sieve / benzene
With pyridine; lithium aluminium tetrahydride; molecular sieve; Mesitol; sulfuric acid; ammonia; oxalic acid; aluminum isopropoxide; sodium hydride; aniline; butanone; In tetrahydrofuran; diethyl ether; benzene;

2322-77-2 Upstream products

  • 14507-49-4
    14507-49-4

    D-13β-ethyl-17β-hydroxy-3-methoxy-gona-2,5(10)-diene

  • 7443-72-3
    7443-72-3

    18-methyl-3-methoxy-1,3,5(10),8-estratetraen-17β-ol

  • 75863-25-1
    75863-25-1

    2-Trimethylsilyl-1-(4-methoxy-2-methylphenyl)prop-2-en-1-on

  • 101025-85-8
    101025-85-8

    13-Ethyl-3-methoxy-6,7:8,9-disecogona-1,3,5(10),7-tetraen-9,17-dion

2322-77-2 Downstream products

  • 799-43-9
    799-43-9

    13β-ethyl-3-methoxy-17α-ethynyl-gona-2,5(10)-dien-17β-ol

  • 797-63-7
    797-63-7

    levonorgestrel

  • 14507-51-8
    14507-51-8

    13β-ethyl-3-methoxy-17α-ethynyl-gona-2,5(10)-dien-17β-ol

  • 4222-96-2
    4222-96-2

    DL-13β-ethyl-gon-5(10)-ene-3,17-dione

Relevant Products

Shopping Cart

Clear Inquiry