920509-27-9
- Product Name:3,5-dichloro-4-((6-chloro-5-isopropylpyridazin-3-yl)oxy)aniline
- Molecular Formula:C13H12Cl3N3O
- Purity:99%
- Molecular Weight:332.617
Product Details;
CasNo: 920509-27-9
Molecular Formula: C13H12Cl3N3O
Reliable factory customized supply 3,5-dichloro-4-((6-chloro-5-isopropylpyridazin-3-yl)oxy)aniline 920509-27-9
- Molecular Formula:C13H12Cl3N3O
- Molecular Weight:332.617
- PSA:61.03000
- LogP:5.51590
920509-27-9 Relevant articles
Substituted pyridazinone compound and application thereof
-
Paragraph 0086-0088; 0091-0092, (2021/04/14)
The invention provides a substituted pyr...
Pyridazinone derivative and application thereof
-
Paragraph 0074-0076; 0080-0082, (2020/11/23)
The invention provides a pyridazinone de...
THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS
-
Paragraph 0366; 0368, (2020/05/02)
Provided herein are compounds, preferabl...
MODULATORS OF THR-β AND METHODS OF USE THEREOF
-
Paragraph 00263; 00265, (2020/11/23)
Disclosed herein are compounds of Formul...
920509-27-9 Process route
-
-
107228-51-3
3,6-dichloro-4-isopropyl-1,2-dihydropyridazine
-
-
5930-28-9
4-amino-2,6-dichlorophenol
-
-
920509-27-9
3,5-dichloro-4-[[6-chloro-5-(propan-2-yl)pyridazin-3-yl]oxy]aniline
| Conditions | Yield |
|---|---|
|
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 90 ℃;
for 6h;
Inert atmosphere;
|
69% |
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 90 ℃;
for 16h;
Time;
Inert atmosphere;
|
63% |
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 90 ℃;
for 16h;
Inert atmosphere;
|
62.44% |
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 120 ℃;
for 3h;
|
61% |
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 90 ℃;
for 24h;
Product distribution / selectivity;
|
50% |
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 20 - 90 ℃;
for 24h;
Inert atmosphere;
|
50% |
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 90 ℃;
Temperature;
|
49% |
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 90 ℃;
for 16h;
Inert atmosphere;
|
|
|
With
copper(l) iodide; potassium carbonate;
In
dimethyl sulfoxide;
at 90 ℃;
for 16h;
|
-
-
107228-51-3
3,6-dichloro-4-isopropyl-1,2-dihydropyridazine
-
-
920509-27-9
3,5-dichloro-4-[[6-chloro-5-(propan-2-yl)pyridazin-3-yl]oxy]aniline
| Conditions | Yield |
|---|---|
|
4-amino-2,6-dichlorophenol;
With
potassium tert-butylate;
In
N,N-dimethyl acetamide;
at 90 ℃;
3,6-dichloro-4-isopropyl-1,2-dihydropyridazine;
In
N,N-dimethyl acetamide;
at 90 ℃;
for 17h;
Product distribution / selectivity;
|
920509-27-9 Upstream products
-
107228-51-3
3,6-dichloro-4-isopropyl-1,2-dihydropyridazine
-
5930-28-9
4-amino-2,6-dichlorophenol
920509-27-9 Downstream products
-
920509-28-0
6-(4-amino-2,6-dichlorophenoxy)-4-isopropyl-pyridazin-3(2H)-one
-
920509-66-6
2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)isoindoline-1,3-dione
-
920509-67-7
2-(3,5-dichloro-4-((5-isopropyl-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)isoindoline-1,3-dione
-
920509-68-8
6-(4-amino-2,6-dichlorophenoxy)-4-isopropyl-2-methyl-2H-pyridazin-3-one
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