61825-94-3

Quality products make an important contribution to long-term revenue and profitability. Cost-effective and customizable Oxaliplatin 61825-94-3 in stock

1.What is the Oxaliplatin ?

A antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA

2.What is the CAS number for Oxaliplatin ?

The CAS number of Oxaliplatin is 61825-94-3.

More information of Oxaliplatin 61825-94-3 are:

3.What are another words for Oxaliplatin ?

Synonyms for Oxaliplatin 61825-94-3:Eloxatin;1-OHP;(1R,2R)-cyclohexane-1,2-diamine; oxalic acid; platinum(+2) cation;Eloxatin (TN);Trans-l-diaminocyclohexane oxalatoplatinum;Platinum, (1,2-cyclohexanediamine-N,N)(ethanedioato(2-)-O,O-, (SP-4-2-(1R-trans))-;Platinum, [ (1R,2R)-1,2-cyclohexanediamine-.kappa.N, .kappa.N][ethanedioato(2-)-.kappa.O1,.kappa.O2]-,(SP-4-2)-;(SP-4-2-(1R-trans))-(1,2-Cyclohexanediamine-N,N)(ethanedioato(2-)-O,O)platinum;RP 54780;Oxalatoplatinum;Oxaliplatin EP5;

4.What is the molecular formula of Oxaliplatin?

The chemical formula of  Oxaliplatin is C8H14N2O4Pt which containing 8 Carbon atoms,14 Hydrogen atoms,2 Nitrogen atoms,4 Oxygen atoms and 1 Platinum atoms,and the molecular weight of  Oxaliplatin is 397.29.

5.What is Oxaliplatin (61825-94-3) used for?

Eloxatin was launched in France for second-line treatment of metastatic colorectal cancer. Oxaliplatin is a second generation platinum drug prepared in three steps from either k2tCl4 or K2Ptl4. It has an antitumor spectrum similar to cisplatin, however, it is more effective against L1210 leukemia and cisplatin resistant L1210. It is also effective against B16 melanoma but has a dose limiting toxicity of peripheral sensory neuropathy that is reversible upon cessation of the drug. The (R,R)- enantiomer has greater activity than the (S,S)-isomer but this is tumor line dependent, e.g., there was no difference found for P-388 or Sarcoma 180. Clinical drug administration based on circadium timing showed it was better tolerated when given 16 h after the onset of light. Oxaliplatin binds to guanineN7 and can lead to bidentate chelation that results in the bending of DNA. This feature is recognized by high mobility group proteins (HMG) which impedes repair reactions and stops replication and transcription.

InChI:InChI=1/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1/rC8H14N2O4Pt/c11-7-8(12)14-15(13-7)9-5-3-1-2-4-6(5)10-15/h5-6H,1-4,9-10H2/t5-,6-/m1/s1

Relevant articles related to Oxaliplatin:

6.Buy Oxaliplatin with the best price .

Golden Pharma Co., Limited is a quality supplier of Oxaliplatin. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Oxaliplatin 61825-94-3.