1226781-44-7
- Product Name：Omarigliptin
- Molecular Formula：C17H20F2N4O3S
- Purity：99%
- Molecular Weight：398.434
Product Details;
CasNo： 1226781-44-7
Molecular Formula： C17H20F2N4O3S
Factory Sells Best Quality Omarigliptin 1226781-44-7 with ISO standards We supply high quality Omarigliptin (MK-3102) (CAS 1226781-44-7), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the Omarigliptin (MK-3102) ?
Omarigliptin (MK-3102) is , while it's Molecular Formula is C17H20F2N4O3S. Omarigliptin is a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes.
What is the CAS number for Omarigliptin (MK-3102) ?
The CAS number of Omarigliptin (MK-3102) is 1226781-44-7.
More information of Omarigliptin (MK-3102) 1226781-44-7 are:
|
Synonyms |
mk-3102; |
|
CAS Number |
1226781-44-7 |
|
Molecular Formula |
C17H20F2N4O3S |
|
Molecular Weight |
398.434 |
|
Density |
1.61±0.1 g/cm3(Predicted) |
|
Boiling Point |
529.4±60.0 °C(Predicted) |
|
PSA |
98.83000 |
|
LogP |
2.86110 |
|
Pka |
9.11±0.60(Predicted) |
What is Omarigliptin (MK-3102) (1226781-44-7) used for?
MK-3102 is a potent, reversible, and competitive inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 1.6 nM; Ki = 0.8 nM). It is selective for DPP-4 over 168 proteases, ion channels, and enzymes with IC50 values greater than 10 μM in all assays. MK-3102 significantly reduces blood glucose levels in a dose-dependent manner in vivo in rats. It also has a long half-life (11 and 22 hours in rat and dog, respectively) making it suitable for once weekly dosing. Clinical trials demonstrate that formulations containing MK-3102 reduce plasma glucose and HbA1c in patients with type 2 diabetes mellitus (T2DM).
Articles related to Omarigliptin (MK-3102):
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Article |
Source |
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A one-pot synthesis of omarigliptin and its analogues through stabilized beta-amino ketone intermediate |
Li, You,Liu, Tongchao,Li, Chungang,Xiong, Bing,Zhao, Dongmei,Cheng, Maosheng,Chen, Guohua,Shen, Jingkang,Chen, Yue-Lei , p. 357 - 363 (2017) |
|
Preparation method for chiral tetrahydropyran derivative |
- Paragraph 0024; 0042; 0044; 0045, (2018/03/26) |
How to get the best price on Omarigliptin (MK-3102)?
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