52763-21-0
- Product Name：Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride
- Molecular Formula：C15H20ClNO3
- Purity：99%
- Molecular Weight：297.782
Product Details;
CasNo： 52763-21-0
Molecular Formula： C15H20ClNO3
Appearance： white to brown crystalline powder
Factory Sells Best Quality Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride 52763-21-0 with USP
- Molecular Formula:C15H20ClNO3
- Molecular Weight:297.782
- Appearance/Colour:white to brown crystalline powder
- Vapor Pressure:1.26E-05mmHg at 25°C
- Melting Point:162 °C (dec.)(lit.)
- Boiling Point:368.6 °C at 760 mmHg
- Flash Point:176.7 °C
- PSA：46.61000
- Density:1.154 g/cm3
- LogP:2.38060
Ethyl N-benzyl-3-oxo-4-piperidine-carboxylate hydrochloride(Cas 52763-21-0) Usage
InChI:InChI=1/C15H19NO3/c1-2-19-15(18)13-8-9-16(11-14(13)17)10-12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3/p+1/t13-/m1/s1
52763-21-0 Relevant articles
Preparation method of N-benzyl-3-oxopiperidine-4-carboxylic acid ethyl ester hydrochloride
-
Paragraph 0006; 0018; 0022-0026; 0030-0034; 0038-0041, (2020/02/10)
The invention provides a preparation met...
Process development and scale-up of a selective α1- adrenoceptor antagonist
Connolly, Terrence J.,Matchett, Michael,Sarma, Keshab
, p. 80 - 87 (2012/12/24)
A synthetic route to a potent and select...
Efficient enantioselective synthesis of the NMDA 2B receptor antagonist Ro 67-8867
Scalone, Michelangelo,Waldmeier, Pius
, p. 418 - 425 (2013/09/06)
An efficient, enantioselective, and scal...
Process for the preparation of ethanesul fonyl-piperidine derivatives
-
, (2008/06/13)
The present invention relates to a new p...
52763-21-0 Process route
-
![4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester](/upload/2026/9/041af819-0c25-425d-9442-a3fe574c321c.png)
-
63876-32-4
4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester
-
-
52763-21-0
ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride
| Conditions | Yield |
|---|---|
|
4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester;
With
sodium ethanolate;
In
toluene;
at 20 - 85 ℃;
for 3.5h;
Large scale;
With
hydrogenchloride;
In
water; toluene;
Large scale;
|
94% |
|
4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester;
With
sodium methylate;
In
ethyl acetate;
for 4h;
Reflux;
Large scale;
With
water; sodium hydroxide;
pH=7 - 8;
Large scale;
With
hydrogenchloride;
pH=1 - 2;
Reagent/catalyst;
Solvent;
Large scale;
|
8.6 kg |
-
-
39514-19-7
ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate
-
-
52763-21-0
ethyl 1-benzyl-3-oxopiperidine-4-carboxylate hydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
ethanol;
at 22 ℃;
for 0.5h;
Inert atmosphere;
Large scale;
|
76.8% |
52763-21-0 Upstream products
-
39514-19-7
ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate
-
2969-81-5
Ethyl 4-bromobutyrate
-
6436-90-4
ethyl 2-(benzylamino)acetate
-
63876-32-4
4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester
52763-21-0 Downstream products
-
26685-45-0
2-benzyl-8-(1,2-dimethylheptyl)-10-hydroxy-5-oxo-1,2,3,4-tetrahydro-5H-[1]benzopyrano[4,3-c]pyridine
-
26685-45-0
2-benzyl-8-(1,2-dimethyl-heptyl)-10-hydroxy-1,2,3,4-tetrahydro-chromeno[4,3-c]pyridin-5-one
-
26685-45-0
2-benzyl-8-(1,2-dimethyl-heptyl)-10-hydroxy-1,2,3,4-tetrahydro-chromeno[4,3-c]pyridin-5-one
-
26685-45-0
2-benzyl-8-(1,2-dimethyl-heptyl)-10-hydroxy-1,2,3,4-tetrahydro-chromeno[4,3-c]pyridin-5-one
Relevant Products
-
Methyl trans-4-aminocyclohexanecarboxylate hydrochlorideCAS：61367-07-5
-
Melengestrol acetateCAS：2919-66-6
-
NestoroneCAS：7759-35-5
