7759-35-5

  • Product Name:Nestorone
  • Molecular Formula:C23H30O4
  • Purity:99%
  • Molecular Weight:370.489
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Product Details;

CasNo: 7759-35-5

Molecular Formula: C23H30O4

Manufacturer Sells Best Quality Nestorone 7759-35-5 with stock

  • Molecular Formula:C23H30O4
  • Molecular Weight:370.489
  • Vapor Pressure:4.2E-10mmHg at 25°C 
  • Melting Point:178-179° 
  • Refractive Index:1.4433 (estimate) 
  • Boiling Point:499.3°Cat760mmHg 
  • Flash Point:216.2°C 
  • PSA:60.44000 
  • Density:1.15g/cm3 
  • LogP:4.18520 

Nestoron(Cas 7759-35-5) Usage

Pharmacokinetics

Elcometrine is a member of the 19-norprogesterone class of pr ogestins. when administered subcuta neously (implant), intravaginally (vaginal ring), or transdermally, elcometrine is an exceptionally potent progestin. It is 100-fold more potent when administered subcutaneously than when delivered orally. Its oral bioavaiability is only 10%,with a half life of just 1 to 2 hours because of rapid metabolism. The C16 methylene functionality substantially increases its affinity for the progesterone receptor.

InChI:InChI=1/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1

7759-35-5 Relevant articles

Method of synthesis of 17-alpha-hydroxy-16-methylene-19-norprogesterone and its derivatives

Mehrhof,Irmscher,Erb,Pohl

, p. 643 - 658 (2007/10/15)

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7759-35-5 Process route

C<sub>24</sub>H<sub>31</sub>BrO<sub>6</sub>

C24H31BrO6

nestorone
7759-35-5

nestorone

Conditions
Conditions Yield
Multistep reaction; (i) aq. CrO3, H2SO4, acetone, (ii) Zn, AcOH;
16-Methylen-17-α-acetoxy-19-nor-progesteron
7759-35-5

16-Methylen-17-α-acetoxy-19-nor-progesteron

Conditions
Conditions Yield
Dihydroxypregnenonacetat (7) (ueber Saeure 8);
3-Pyrrolidino-16-α-17-α-epoxy-16-β-methyl-19-nor-3,5-pregnadien-20-on, Acetanhydrid;
16-Methylen-17-α-acetoxy-19-hydroxyprogesteron, 1) sek. Amin, 2) CH3COOH, CH3COONa;

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