7759-35-5
- Product Name:Nestorone
- Molecular Formula:C23H30O4
- Purity:99%
- Molecular Weight:370.489
Product Details;
CasNo: 7759-35-5
Molecular Formula: C23H30O4
Manufacturer Sells Best Quality Nestorone 7759-35-5 with stock
- Molecular Formula:C23H30O4
- Molecular Weight:370.489
- Vapor Pressure:4.2E-10mmHg at 25°C
- Melting Point:178-179°
- Refractive Index:1.4433 (estimate)
- Boiling Point:499.3°Cat760mmHg
- Flash Point:216.2°C
- PSA:60.44000
- Density:1.15g/cm3
- LogP:4.18520
Nestoron(Cas 7759-35-5) Usage
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Pharmacokinetics |
Elcometrine is a member of the 19-norprogesterone class of pr ogestins. when administered subcuta neously (implant), intravaginally (vaginal ring), or transdermally, elcometrine is an exceptionally potent progestin. It is 100-fold more potent when administered subcutaneously than when delivered orally. Its oral bioavaiability is only 10%,with a half life of just 1 to 2 hours because of rapid metabolism. The C16 methylene functionality substantially increases its affinity for the progesterone receptor. |
InChI:InChI=1/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1
7759-35-5 Relevant articles
Method of synthesis of 17-alpha-hydroxy-16-methylene-19-norprogesterone and its derivatives
Mehrhof,Irmscher,Erb,Pohl
, p. 643 - 658 (2007/10/15)
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7759-35-5 Process route
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C24H31BrO6
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7759-35-5
nestorone
| Conditions | Yield |
|---|---|
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Multistep reaction;
(i) aq. CrO3, H2SO4, acetone, (ii) Zn, AcOH;
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7759-35-5
16-Methylen-17-α-acetoxy-19-nor-progesteron
| Conditions | Yield |
|---|---|
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Dihydroxypregnenonacetat (7) (ueber Saeure 8);
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3-Pyrrolidino-16-α-17-α-epoxy-16-β-methyl-19-nor-3,5-pregnadien-20-on, Acetanhydrid;
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16-Methylen-17-α-acetoxy-19-hydroxyprogesteron, 1) sek. Amin, 2) CH3COOH, CH3COONa;
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