What is the Dexamethasone palmitate?

Dexamethasone palmitate is , while it's Molecular Formula is C38H59 F O6. A corticosteroid prodrug for the treatment of eye disorders.

What is the CAS number for Dexamethasone palmitate?

The CAS number of Dexamethasone palmitate is 14899-36-6.

What is Dexamethasone palmitate (14899-36-6) used for?

Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).InChI:InChI=1/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1

What is the Dexamethasone palmitate?

Dexamethasone palmitate is , while it's Molecular Formula is C38H59 F O6. A corticosteroid prodrug for the treatment of eye disorders.

What is the CAS number for Dexamethasone palmitate?

The CAS number of Dexamethasone palmitate is 14899-36-6.

What is Dexamethasone palmitate (14899-36-6) used for?

Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).InChI:InChI=1/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1

Product classification

Hormones and steriods major pro

Medroxyprogesterone acetate intermediates

Progesterone intermediate

Cyproterone acetate intermediate

Deflazacort intermediate

Desogestrel intermediate

Finasteride intermediate

Steroid & Hormone Products
Major Products

Rocuronium bromide intermediate

Ubrogepant intermediate

Rimegepant intermediate

Indacaterol intermedaite

Dapagliflozin intermediate

Pharmaceutical Products

Other
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14899-36-6

Product Name：Dexamethasone palmitate
Molecular Formula：C38H59 F O6
Purity：99%
Molecular Weight：630.881

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Product Details;

CasNo： 14899-36-6

Molecular Formula： C38H59 F O6

Factory supply good quality Dexamethasone palmitate 14899-36-6 with stock

Molecular Formula:C38H59 F O6
Molecular Weight:630.881
Vapor Pressure:2.69E-23mmHg at 25°C
Melting Point:60-65 °C
Boiling Point:710.1°Cat760mmHg
PKA:11.99±0.70(Predicted)
Flash Point:383.2°C
PSA：100.90000
Density:1.12
LogP:7.92790

Dexamethasone palmitate(Cas 14899-36-6) Usage

Biochem/physiol Actions

Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.

InChI:InChI=1/C38H59FO6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(43)45-26-33(42)38(44)27(2)23-31-30-20-19-28-24-29(40)21-22-35(28,3)37(30,39)32(41)25-36(31,38)4/h21-22,24,27,30-32,41,44H,5-20,23,25-26H2,1-4H3/t27-,30+,31+,32+,35+,36+,37+,38+/m1/s1