1454848-24-8
- Product Name:tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
- Molecular Formula:
- Purity:99%
- Molecular Weight:329.197
Product Details;
CasNo: 1454848-24-8
Cosmetics Grade tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate 1454848-24-8 For Sale with Good Price
- Molecular Formula:C12H17BrN4O2
- Molecular Weight:329.197
- Boiling Point:441.1±45.0 °C(Predicted)
- PKA:-1.77±0.70(Predicted)
- Density:1.38±0.1 g/cm3(Predicted)
1454848-24-8 Relevant articles
Synthesis method of glatianide intermediate
-
Paragraph 0048; 0068-0070, (2021/08/25)
The invention provides a synthesis metho...
Synthesis of 1, 3, 4, 5-tetrasubstituted 1H-pyrazole derivative
-
, (2021/09/04)
The invention relates to synthesis of an...
Benzoxadiazepine tetradecene derivative and application thereof
-
Paragraph 0074-0077; 0094-0095, (2020/07/15)
The invention discloses a benzoxadiazepi...
MACROCYCLE AND COMPOSITION COMPRISING THEREOF
-
Paragraph 0068; 0071, (2019/01/04)
A macrocycle represented by formula (I) ...
1454848-24-8 Process route
-
-
tert-butyl [(4-bromo-5-carbamoyl-1-methyl-1H-pyrazol-3-yl)methyl]methylcarbamate
-
-
1454848-24-8
((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
|
With
triethylamine; trifluoroacetic anhydride;
In
dichloromethane;
at 0 - 5 ℃;
for 2h;
|
89.7% |
|
With
triethylamine; trifluoroacetic anhydride;
In
dichloromethane;
at -5 - 0 ℃;
for 1.5h;
|
87% |
|
With
triethylamine; trifluoroacetic acid;
In
dichloromethane;
at -5 - 0 ℃;
for 1.5h;
|
71% |
|
With
triethylamine; trifluoroacetic anhydride;
In
dichloromethane;
at -5 - 0 ℃;
for 1.5h;
|
2.3 g |
-
-
24424-99-5
di-tert-butyl dicarbonate
-
-
4-bromo-1-methyl-3-[(methylamino)methyl]-1H-pyrazole-5-carbonitrile
-
-
1454848-24-8
((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
|
With
carbon dioxide;
In
dichloromethane;
at 20 ℃;
for 3.58333h;
Inert atmosphere;
|
100% |
|
In
dichloromethane;
at 20 - 30 ℃;
for 3h;
Inert atmosphere;
|
96% |
|
With
triethylamine;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
|
95% |
|
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 0.5h;
|
81.7% |
1454848-24-8 Upstream products
-
5744-40-1
ethyl 1,3-dimethylpyrazole-5-carboxylate
-
24424-99-5
di-tert-butyl dicarbonate
-
1005641-22-4
4-bromo-1,3-dimethyl-1H-pyrazole-5-carboxamide
-
306936-77-6
1,3-dimethyl-1H-pyrazole-5-carbonitrile
1454848-24-8 Downstream products
-
1454848-70-4
tert-butyl[(5-cyano-1-methyl-1Hpyrazol-3-yl)methyl]methylcarbamate
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