259793-88-9
- Product Name：6-Bromo-3-hydroxypyrazine-2-carboxamide
- Molecular Formula：C5H4BrN3O2
- Purity：99%
- Molecular Weight：218.01
Product Details;
CasNo： 259793-88-9
Molecular Formula： C5H4BrN3O2
Quality Manufacturer Supply Wholesale 6-Bromo-3-hydroxypyrazine-2-carboxamide 259793-88-9 Cheapest Price
- Molecular Formula:C5H4BrN3O2
- Molecular Weight:218.01
- PKA:9.02±0.60(Predicted)
- PSA：89.10000
- Density:2.23±0.1 g/cm3(Predicted)
- LogP:0.74390
259793-88-9 Relevant articles
Preparation method of favipiravir
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Paragraph 0031-0035, (2021/02/10)
The invention relates to the technical f...
6-bromo-3-hydroxy-2-pyrazine amide preparation method (by machine translation)
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Paragraph 0026; 0027; 0028; 0029, (2016/11/02)
The invention belongs to the field of ch...
259793-88-9 Process route
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55321-99-8
3-oxo-3,4-dihydropyrazine-2-carboxamide
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259793-88-9
6-bromo-3-oxo-3,4-dihydro-2-pyrazinecarboxamide
| Conditions | Yield |
|---|---|
|
With
pyridine; bromine;
In
N,N-dimethyl-formamide;
at 80 - 100 ℃;
for 3h;
|
62.1% |
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27825-20-3
3-hydroxypyrazine-2-carboxylic acid methyl ester
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-
259793-88-9
6-bromo-3-oxo-3,4-dihydro-2-pyrazinecarboxamide
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methyl-6-bromo-3-oxo-3,4-dihydro-2-pyrazinecarboxylate
| Conditions | Yield |
|---|---|
|
With
bromine;
In
acetonitrile;
at 27 ℃;
for 1h;
Overall yield = 65 %; Overall yield = 300 g;
|
259793-88-9 Upstream products
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27825-20-3
3-hydroxypyrazine-2-carboxylic acid methyl ester
-
21874-61-3
3-hydroxy-6-bromopyrazine-2-carboxylic acid methyl ester
-
55321-99-8
3-oxo-3,4-dihydropyrazine-2-carboxamide
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