1125-78-6

  • Product Name:5,6,7,8-tetrahydro-2-naphthol
  • Molecular Formula:C10H12O
  • Purity:99%
  • Molecular Weight:148.205
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Product Details;

CasNo: 1125-78-6

Molecular Formula: C10H12O

Appearance: beige crystalline mass

Buy Reliable Quality 99% Pure 5,6,7,8-tetrahydro-2-naphthol 1125-78-6 Customized Supply

  • Molecular Formula:C10H12O
  • Molecular Weight:148.205
  • Appearance/Colour:beige crystalline mass 
  • Melting Point:59-61 °C(lit.) 
  • Refractive Index:1.5000 (estimate) 
  • Boiling Point:275.5 °C at 760 mmHg 
  • PKA:10.48(at 25℃) 
  • Flash Point:131.8 °C 
  • PSA:20.23000 
  • Density:1.1 g/cm3 
  • LogP:2.27100 

5,6,7,8-Tetrahydro-2-naphthol(Cas 1125-78-6) Usage

Chemical Properties

beige crystalline mass

Uses

5,6,7,8-Tetrahydro-2-naphthol was used as a model compound in the study of photochemical transformation of 17β-estradiol (natural estrogenic steroid) and 17α-ethinylestradiol (synthetic oral contraceptive).

Definition

ChEBI: A member of the class tetralins that is 1,2,3,4-tetrahydronaphthalene which is substituted at position 6 by a hydroxy group.

Synthesis Reference(s)

The Journal of Organic Chemistry, 45, p. 5002, 1980 DOI: 10.1021/jo01312a044

InChI:InChI=1/C10H12O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h5-7,11H,1-4H2

1125-78-6 Relevant articles

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van Tamelen,Proost

, p. 3632 (1954)

-

-

Dauben,McKusick,Mueller

, p. 4179,4181 (1948)

-

Reduction of 1,1'-binaphthyls to octahydro-1,1'-binaphthyl derivatives with Raney Ni-Al alloy in aqueous solution

Guo,Ding

, p. 10061 - 10064 (2000)

Reduction of BINOL, BINAM and NOBIN with...

-

Adkins,Krsek

, p. 412 (1948)

-

-

Arnold,Evans

, p. 556 (1940)

-

-

Stork

, p. 576,578 (1947)

-

Partial ring hydrogenation of naphthols over supported metal catalysts in supercritical carbon dioxide solvent

Mine, Eiichi,Haryu, Eiji,Arai, Kunio,Sato, Takafumi,Sato, Osamu,Sasaki, Akiyoshi,Rode, Chandrashekhar V.,Shirai, Masayuki

, p. 782 - 783 (2005)

Selective ring hydrogenation of naphthol...

-

Shah,Tilak,Venkataraman

, p. 142,146 (1948)

-

-

Hunter,Nathan

, p. 2064 (1947)

-

Selective partial hydrogenation of hydroxy aromatic derivatives with palladium nanoparticles supported on hydrophilic carbon

Makowski, Philippe,Demir Cakan, Rezan,Antonietti, Markus,Goettmann, Frederic,Titirici, Maria-Magdalena

, p. 999 - 1001 (2008)

Selective hydrogenation of phenol to cyc...

HYDROGENATION AND HYDROGENOLYSIS. XVII. THE SELECTIVITIES OF PLATINUM GROUP METALS IN CATALYTIC HYDROGENATION OF 2-NAPHTHOL AND TETRAHYDRO-2-NAPHTHOLS.

Nishimura,Ohbuchi,Ikeno,Okada

, p. 2557 - 2564 (1984)

Catalytic hydrogenation of 2-naphthol (N...

A mild and practical method for deprotection of aryl methyl/benzyl/allyl ethers with HPPh2andtBuOK

Pan, Wenjing,Li, Chenchen,Zhu, Haoyin,Li, Fangfang,Li, Tao,Zhao, Wanxiang

, p. 7633 - 7640 (2021/09/22)

A general method for the demethylation, ...

Mild and Selective Rhodium-Catalyzed Transfer Hydrogenation of Functionalized Arenes

Wang, Yuhan,Chang, Zhiqian,Hu, Yan,Lin, Xiao,Dou, Xiaowei

supporting information, p. 1910 - 1914 (2021/03/08)

Diboron-mediated rhodium-catalyzed trans...

Tuning the Reactivity of Peroxo Anhydrides for Aromatic C-H Bond Oxidation

Pilevar, Afsaneh,Hosseini, Abolfazl,?ekutor, Marina,Hausmann, Heike,Becker, Jonathan,Turke, Kevin,Schreiner, Peter R.

, p. 10070 - 10079 (2018/09/06)

Phenol moieties are key structural motif...

Regioselective and Chemoselective Reduction of Naphthols Using Hydrosilane in Methanol: Synthesis of the 5,6,7,8-Tetrahydronaphthol Core

He, Yuan,Tang, Jinghua,Luo, Meiming,Zeng, Xiaoming

supporting information, p. 4159 - 4163 (2018/07/29)

A regioselective and chemoselective meth...

1125-78-6 Process route

5,6,7,8-tetrahydronaphthalen-2-yl benzoate
3574-36-5

5,6,7,8-tetrahydronaphthalen-2-yl benzoate

5,6,7,8-Tetrahydro-2-naphthol
1125-78-6

5,6,7,8-Tetrahydro-2-naphthol

N-butylbenzamide
2782-40-3

N-butylbenzamide

Conditions
Conditions Yield
With N-butylamine; In benzene; for 22h; Yield given; Ambient temperature;
5,6,7,8-tetrahydronaphthalen-2-yl benzoate
3574-36-5

5,6,7,8-tetrahydronaphthalen-2-yl benzoate

N-butylamine
109-73-9,85404-21-3

N-butylamine

5,6,7,8-Tetrahydro-2-naphthol
1125-78-6

5,6,7,8-Tetrahydro-2-naphthol

N-butylbenzamide
2782-40-3

N-butylbenzamide

Conditions
Conditions Yield
In benzene; for 22h; Yields of byproduct given; Ambient temperature;

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