177034-57-0
- Product Name：4-Isopropoxyethoxymethyl-1-Hydroxybenzene
- Molecular Formula：C12H18O3
- Purity：99%
- Molecular Weight：210.273
Product Details;
CasNo： 177034-57-0
Molecular Formula： C12H18O3
Appearance： pale yellow oil
Buy High Quality Top Purity 4-Isopropoxyethoxymethyl-1-Hydroxybenzene 177034-57-0 Competitive Price
- Molecular Formula:C12H18O3
- Molecular Weight:210.273
- Appearance/Colour:pale yellow oil
- Vapor Pressure:0mmHg at 25°C
- Refractive Index:1.509
- Boiling Point:308.742 °C at 760 mmHg
- PKA:9.66±0.15(Predicted)
- Flash Point:140.523 °C
- PSA：38.69000
- Density:1.052 g/cm3
- LogP:2.33380
4-Isopropoxyethoxymethylphenol(Cas 177034-57-0) Usage
|
Chemical Properties |
Pale Yellow Oil |
|
Uses |
An intermediate for the synthesis of Bisoprolol |
InChI:InChI=1/C12H18O3/c1-10(2)15-8-7-14-9-11-3-5-12(13)6-4-11/h3-6,10,13H,7-9H2,1-2H3
177034-57-0 Relevant articles
Bisoprolol-based 18F-PET tracer: Synthesis and preliminary in vivo validation of β1-blocker selectivity for β1-adrenergic receptors in the heart
Chang, Dong-Jo,Jung, Yerim,Kang, Julie,Kim, Dong-Yeon,More, Kunal N.,Pyo, Ayoung
, (2021)
The selectivity of a drug toward various...
NOVEL AROMATIC COMPOUND AND USE THEREOF
-
Paragraph 0893-0895, (2016/08/17)
Provided is a compound showing a bone fo...
A simple and an efficient indium trichloride catalyzed benzyl etherification
Bhaskar,Solomon,Babu,Muralidharan,Perumal, Paramasivan T.
scheme or table, p. 795 - 801 (2011/01/04)
An efficient method has been developed f...
A NOVEL PROCESS FOR THE SYNTHESIS OF BISODPROLOL AND ITS INTERMEDIATE
-
Page/Page column 5; 8-9, (2010/11/27)
This invention relates to a manufacturin...
177034-57-0 Process route
-
-
109-59-1
2-(1-methylethoxy)-ethanol
-
-
623-05-2
(4-hydroxyphenyl)methanol
-
-
177034-57-0
4-(2-isopropoxy-ethoxymethyl)-phenol
| Conditions | Yield |
|---|---|
|
With
indium(III) chloride;
at 80 ℃;
for 3.25h;
Neat (no solvent);
|
87% |
|
With
Dowex 50WX8 resin,;
at 20 ℃;
for 12h;
|
69% |
|
With
ytterbium(III) triflate;
at 80 ℃;
for 1.5h;
|
67% |
|
With
cation exchange resin AG 50W-X8;
Heating;
|
|
|
With
polymer supported SO3H;
at 0 - 20 ℃;
for 17h;
Amberlyst-15 resin
|
-
-
109-59-1
2-(1-methylethoxy)-ethanol
-
-
623-05-2
(4-hydroxyphenyl)methanol
-
-
76890-93-2
4,4’-dihydroxydibenzyl ether
-
-
177034-57-0
4-(2-isopropoxy-ethoxymethyl)-phenol
| Conditions | Yield |
|---|---|
|
With
ytterbium(III) triflate;
In
acetonitrile;
at 80 ℃;
for 5h;
|
85% 4% |
177034-57-0 Upstream products
-
109-59-1
2-(1-methylethoxy)-ethanol
-
623-05-2
(4-hydroxyphenyl)methanol
177034-57-0 Downstream products
-
66722-57-4
2-((4-((2-isopropoxyethoxy)methyl)phenoxy)methyl)oxirane
-
99103-03-4
(-)-Bisoprolol
-
208523-18-6
(S)-(-)-bisoprolol hemifumarate
-
111051-40-2
(+)-Bisoprolol
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-
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