496-16-2
- Product Name:2,3-dihydrobenzofuran
- Molecular Formula:C8H8O
- Purity:99%
- Molecular Weight:120.151
Product Details;
CasNo: 496-16-2
Molecular Formula: C8H8O
Appearance: colorless to light yellow liquid
Factory Supply 2,3-dihydrobenzofuran 496-16-2 Buy On Stock
- Molecular Formula:C8H8O
- Molecular Weight:120.151
- Appearance/Colour:colorless to light yellow liquid
- Vapor Pressure:0.836mmHg at 25°C
- Melting Point:-21 °C
- Refractive Index:n20/D 1.549(lit.)
- Boiling Point:188.2 °C at 760 mmHg
- Flash Point:66.7 °C
- PSA:9.23000
- Density:1.096 g/cm3
- LogP:1.62150
2,3-Dihydrobenzofuran(Cas 496-16-2) Usage
Chemical Properties |
Colorless to light yellow liqui |
Uses |
2,3-dihydrobenzofuran is widely used in the synthesis of tricyclic compounds and is also an intermediate raw material for the synthesis of some important drugs. It is used in the synthesis of antitumor agents benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, etc. |
Definition |
ChEBI: 2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran. It has a role as a metabolite. |
General Description |
Biotransformation of 2,3-dihydrobenzofuran using intact cells of Pseudomonas putida UV4 has been investigated. 2,3-Dihydrobenzofuran is the intermediate formed during catalytic hydrodeoxygenation of benzofuran. |
496-16-2 Relevant articles
Stereoselective cyclizations mediated by functionalized organomagnesium reagents and catalyzed by cobalt or copper salts
Kneisel, Florian F.,Monguchi, Yasunari,Knapp, Kolja M.,Zipse, Hendrik,Knochel, Paul
, p. 4875 - 4879 (2002)
The iodine-magnesium exchange reaction w...
A Novel Cyclodehydration Reaction of Hydroxy-phenols using Imidate Esters as Leaving Groups
Procopiou, Panayiotis A.,Brodie, Alastair C.,Deal, Martyn J.,Hayman, David F.
, p. 7483 - 7486 (1993)
A mild, efficient and stereospecific int...
A novel catalyst Pd@ompg-C3N4 for highly chemoselective hydrogenation of quinoline under mild conditions
Gong, Yutong,Zhang, Pengfei,Xu, Xuan,Li, Yi,Li, Haoran,Wang, Yong
, p. 272 - 280 (2013)
Polymeric mesoporous carbon graphitic ni...
Organometallic Synthesis of Bimetallic Cobalt-Rhodium Nanoparticles in Supported Ionic Liquid Phases (CoxRh100?x@SILP) as Catalysts for the Selective Hydrogenation of Multifunctional Aromatic Substrates
Rengshausen, Simon,Van Stappen, Casey,Levin, Natalia,Tricard, Simon,Luska, Kylie L.,DeBeer, Serena,Chaudret, Bruno,Bordet, Alexis,Leitner, Walter
, (2020/12/22)
The synthesis, characterization, and cat...
Heterogeneous Hydrogenation of Quinoline Derivatives Effected by a Granular Cobalt Catalyst
Timelthaler, Daniel,Topf, Christoph
, (2021/11/22)
We communicate a convenient method for t...
Boosting homogeneous chemoselective hydrogenation of olefins mediated by a bis(silylenyl)terphenyl-nickel(0) pre-catalyst
Lücke, Marcel-Philip,Yao, Shenglai,Driess, Matthias
, p. 2909 - 2915 (2021/03/14)
The isolable chelating bis(N-heterocycli...
Preparation of NiCu Alloy Catalyst for the Hydrodeoxygenation of Benzofuran
Zhu, Tianhan,Song, Hua,Li, Feng,Chen, Yanguang
, p. 1670 - 1682 (2020/10/21)
A series of bimetallic NixCu(10-x)/SiO2 ...
496-16-2 Process route
-
-
271-89-6
1-benzofurane
-
-
90-00-6
o-Hydroxyethylbenzene
-
-
496-16-2
2.3-dihydrobenzofuran
-
-
1678-91-7
ethyl-cyclohexane
-
-
100-41-4,27536-89-6
ethylbenzene
Conditions | Yield |
---|---|
With
hydrogen;
VN;
In
tetralin;
at 369.9 ℃;
for 60h;
under 23251.8 Torr;
Product distribution;
investigation of hydrodeoxygenation; different catalysts;
|
-
-
271-89-6
1-benzofurane
-
-
496-16-2
2.3-dihydrobenzofuran
-
-
1003-64-1
ethylidenecyclohexane
Conditions | Yield |
---|---|
With
hydrogen;
In
decane;
at 200 ℃;
for 2.33333h;
under 38787.1 Torr;
Kinetics;
Catalytic behavior;
|
496-16-2 Upstream products
-
1-benzofurane
-
2-Phenoxyethanol
-
1-(2-bromoethoxy)-2-chlorobenzene
-
1-bromo-2-(2-bromoethoxy)benzene
496-16-2 Downstream products
-
2,3-dihydro-benzofuran-5-carbaldehyde
-
ethyl 2( 2,3-dihydro-1-benzofuran-5-yl)oxoacetate
-
1-(2,3-dihydrobenzofuran-5-yl)ethanone
-
1-(2,3-dihydro-benzofuran-5-yl)-2-phenyl-ethanone
Relevant Products
-
Methyl trans-4-aminocyclohexanecarboxylate hydrochloride
CAS:61367-07-5
-
4-Aminocyclohexaneethanol
CAS:857831-26-6