923288-90-8
- Product Name:Nilotinib HCl
 - Molecular Formula:C28H25ClF3N7O2
 - Purity:99%
 - Molecular Weight:584
 
Product Details;
CasNo: 923288-90-8
Molecular Formula: C28H25ClF3N7O2
Appearance: White solid
Buy Nilotinib HCl 923288-90-8 Quality Factory Supply with Efficient Delivery
- Molecular Formula:C28H25ClF3N7O2
 - Molecular Weight:584
 - Appearance/Colour:White solid
 - PSA:101.11000
 - LogP:6.81280
 
923288-90-8 Relevant articles
CRYSTALLINE FORMS OF 4-METHYL-N-[3-(4-METHYL-IMIDAZOL-1-YL)-5-TRIFLUOROMETHYL-PHENYL]-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-BENZAMIDE
-
Page/Page column 28, (2008/06/13)
Crystalline forms of 4-methyl-N-[3-(4-me...
SALTS OF 4-METHYL-N-[3-(4-METHYL-IMIDAZOL-1-YL)-5-TRIFLUOROMETHYL-PHENYL]-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-BENZAMIDE
-
Page/Page column 10-11, (2008/06/13)
Salts of 4-methyl-N-[3-(4-methyl-imidazo...
923288-90-8 Process route
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                                         - 
                                        641571-10-0
                                        
nilotinib
 
                                - 
                                        
                                            
                                         - 
                                        923288-90-8
                                        
4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide monohydrochloride monohydrate
 
| Conditions | Yield | 
|---|---|
| 
                                        
                                         
                                            
                                                
                                            
                                            With 
                                            
                                            
                                                
                                                    hydrogenchloride; water; 
                                            
                                            
                                                
                                            
                                            In 
                                            
                                                methanol; 
                                            
                                            
                                            
                                                
                                                            at 30 - 50 ℃;
                                                            
                                                            for 0.75h;
                                                            
                                                Product distribution / selectivity;
                                                            
                                            
                                         
                                        
                                     | 
                                    |
| 
                                        
                                         
                                            
                                                
                                            
                                            With 
                                            
                                            
                                                
                                                    hydrogenchloride; water; 
                                            
                                            
                                                
                                            
                                            In 
                                            
                                                methanol; 
                                            
                                            
                                            
                                                
                                                            at 23 - 50 ℃;
                                                            
                                                            for 4.5h;
                                                            
                                            
                                         
                                        
                                     | 
                                    |
| 
                                        
                                         
                                            
                                                
                                            
                                            With 
                                            
                                            
                                                
                                                    hydrogenchloride; water; 
                                            
                                            
                                                
                                            
                                            In 
                                            
                                                methanol; 
                                            
                                            
                                            
                                                
                                                            at -10 - 64 ℃;
                                                            
                                                            for 2.5h;
                                                            
                                                Product distribution / selectivity;
                                                            
                                            
                                         
                                        
                                     | 
                                    
923288-90-8 Upstream products
- 
                           
                                641571-10-0
                                nilotinib
 
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