753498-25-8

  • Product Name:Indacaterol Maleate
  • Molecular Formula:C24H28N2O3.C4H4O4
  • Purity:99%
  • Molecular Weight:508.571
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Product Details;

CasNo: 753498-25-8

Molecular Formula: C24H28N2O3.C4H4O4

Appearance: White Solid

Factory Supply High Purity Indacaterol Maleate 753498-25-8 In Bulk Supply

  • Molecular Formula:C4H4O4*C24H28N2O3
  • Molecular Weight:508.571
  • Appearance/Colour:White Solid 
  • Melting Point:195-197°C (dec.) 
  • PSA:160.21000 
  • LogP:3.66390 

753498-25-8 Relevant articles

Preparation method of indacaterol and salt thereof

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Paragraph 0059-0060; 0063-0064, (2020/11/01)

The invention relates to a preparation m...

INHALABLE FORMULATION OF A SOLUTION CONTAINING INDACATEROL MALEATE AND GLYCOPYRRONIUM BROMIDE

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Paragraph 0078-0080, (2020/12/13)

The present invention discloses a liquid...

IMPROVED PROCESS FOR THE PREPARATION OF INDACATEROL MALEATE

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, (2020/10/19)

An improved process for the preparation ...

A maleic acid yin dutrow intermediate and its preparation and use

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Paragraph 0081; 0083, (2019/05/16)

The invention relates to maleic acid yin...

753498-25-8 Process route

5,6-diethyl-2,3-dihydro-1H-inden-2-amine
312753-70-1

5,6-diethyl-2,3-dihydro-1H-inden-2-amine

(2E)-but-2-enedioic acid
110-17-8,26099-09-2

(2E)-but-2-enedioic acid

Indacaterol fumarate
753498-25-8

Indacaterol fumarate

C<sub>4</sub>H<sub>4</sub>O<sub>4</sub>*C<sub>31</sub>H<sub>34</sub>N<sub>2</sub>O<sub>3</sub>

C4H4O4*C31H34N2O3

C<sub>4</sub>H<sub>4</sub>O<sub>4</sub>*C<sub>49</sub>H<sub>49</sub>N<sub>3</sub>O<sub>6</sub>

C4H4O4*C49H49N3O6

Conditions
Conditions Yield
(R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone; 5,6-diethyl-2,3-dihydro-1H-inden-2-amine; In diethylene glycol dimethyl ether; at 110 ℃; for 15h;
(2E)-but-2-enedioic acid; Product distribution / selectivity;
68.7%
7.8%
12.4%
5,6-diethyl-2,3-dihydro-1H-inden-2-amine
312753-70-1

5,6-diethyl-2,3-dihydro-1H-inden-2-amine

maleic acid
110-16-7,26099-09-2

maleic acid

indacaterol maleate
753498-25-8

indacaterol maleate

C<sub>4</sub>H<sub>4</sub>O<sub>4</sub>*C<sub>31</sub>H<sub>34</sub>N<sub>2</sub>O<sub>3</sub>

C4H4O4*C31H34N2O3

C<sub>4</sub>H<sub>4</sub>O<sub>4</sub>*C<sub>49</sub>H<sub>49</sub>N<sub>3</sub>O<sub>6</sub>

C4H4O4*C49H49N3O6

Conditions
Conditions Yield
(R)-5-(2-oxiranyl)-8-benzyloxy-2(1H)-quinolinone; 5,6-diethyl-2,3-dihydro-1H-inden-2-amine; In diethylene glycol dimethyl ether; at 110 ℃; for 15h;
maleic acid; Product distribution / selectivity;
68.7%
7.8%
12.4%

753498-25-8 Upstream products

  • 312753-06-3
    312753-06-3

    indacaterol

  • 110-16-7
    110-16-7

    maleic acid

  • 753498-41-8
    753498-41-8

    5-[(R)-2-(5,6-diethylindan-2-ylamino)-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one benzoate

  • 312753-70-1
    312753-70-1

    5,6-diethyl-2,3-dihydro-1H-inden-2-amine

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